KCC2の発現調節におけるBDNF-TrkB経路についてまとめたレビューを執筆しました。
Toda Takuya, Kazuto Ishida, Hiroshi Kiyama, Toshihide Yamashita, and Sachiko Lee. Down-regulation of KCC2 expression and phosphorylation in motoneurons and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity.
PLoS One. December 29, 2014. DOI: 10.1371/journal.pone.0114328
http://dx.plos.org/10.1371/journal.pone.0114328
Sachiko
Lee, Takuya Toda, Hiroshi Kiyama, and Toshihide Yamashita.(2014) Weakened rate-dependent depression of Hoffmann's reflex and increased motoneuron hyperactivity after motor cortical
infarction in mice. Cell Death and Disease.
2014 Jan 16;5:e1007. doi: 10.1038/cddis.2013.544.