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190409_Role of the BDNF-TrkB pathway in KCC2 regulation and rehabilitatino following neuronal injury: a mini review

KCC2の発現調節におけるBDNF-TrkB経路についてまとめたレビューを執筆しました。


脊髄における痙縮病態についての論文

Toda Takuya, Kazuto Ishida, Hiroshi Kiyama, Toshihide Yamashita, and Sachiko Lee. Down-regulation of KCC2 expression and phosphorylation in motoneurons and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity. PLoS One. December 29, 2014. DOI: 10.1371/journal.pone.0114328

http://dx.plos.org/10.1371/journal.pone.0114328

 


2013年12月9日 名古屋で立ち上げた研究が論文になりました。

Sachiko Lee, Takuya Toda, Hiroshi Kiyama, and Toshihide Yamashita.(2014) Weakened rate-dependent depression of Hoffmann's reflex and increased motoneuron hyperactivity after motor cortical infarction in mice. Cell Death and Disease.
2014 Jan 16;5:e1007. doi: 10.1038/cddis.2013.544.